ADME Toxicology Testing Market 2022 New Investment Projects Review
ADME stands for
absorption, distribution, metabolism and elimination, a pharmacokinetics and
pharmacology term that describes the disposition of a compound or a drug inside
the human body. The four processes represent the effect of a particular drug on
human tissues. ADME toxicology test is conducted for assistance with
development of new drugs. In traditional drug development process, toxicity and
efficacy testing is conducted in in-vivo environment which is the major reason
for late stage drug failure in human body owing to the genetic and anatomical
difference in humans and animals. ADME Toxicology Testing successfully
eliminates this barrier and hence, it is being rapidly adopted for drug
development practices globally. Establishment of high throughput ADME profiling
assays enables effective prioritization of drug candidates or leads based on
their biopharmaceutical properties. This can not only improve the overall
quality of drug candidates but also considerably shorten the drug discovery and
development process.
ADME Toxicology Testing can be broadly classified in terms of technology into in-silico
testing, in-vitro testing and in-vivo testing. In vitro testing procedures are
performed outside of a living organism in a controlled environment. In in-vivo
studies, testing is conducted using a whole living organism in the form of
animal studies or clinical trials. In-silico studies refer to a study conducted
on a computer or via computer simulation. In-vitro testing is being
increasingly preferred lately due to rising ethical concerns regarding animal
use in clinical trials. In-silico technologies are also witnessing increased
acceptance due to their cost effective nature and higher throughput ADME
screening capability.
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Some of the key factors contributing to the
growth of global ADME Toxicology Testing market are rising adoption of ADME
Toxicology Testing by pharmaceutical and biotechnology companies and increased
demand for cell-based assays in drug discovery. As ADME testing has proven to
be an efficient time and cost curbing alternative for traditional testing
procedures, the market will witness favorable growth owing to escalating
acceptance ADME Toxicology Testing in coming years. However lack of in-vitro
models to detect immune-stimulation and autoimmunity can hamper the market
growth to some extent.
Major Market Players
Ø
Bio-Rad Laboratories, Inc.
Ø
Agilent Technologies, Inc.
Ø
Dassault System SE
Ø
Beckman Coulter, Inc.
Ø
Cyprotex PLC
Ø
Thermo Fisher Scientific Inc.
Ø
Optivia Biotechnology Inc.
ADME Toxicology Testing
Market Segmentation
By Technology:
- In-silico Testing
- In-vitro Testing
- In-vivo Testing
By Region:
- North America
o
U.S
o
Canada
o
Mexico
- Europe
o
Germany
o
France
o
UK
o
Italy
o
Spain
o
Rest of Europe
- Asia-Pacific
o
Japan
o
China
o
Australia
o
India
o
South Korea
o
Rest of Asia-Pacific
- Rest of the World
o
Brazil
o
South Africa
o
Saudi Arabia
o
Turkey
o
United Arab Emirates
o
Others
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