Preimplantation Genetic Testing Market Trends and 2022 Forecast

Global Preimplantation Genetic Testing refers to the genetic analysis of a single cell from an eight-cell embryo which is done in conjunction with in vitro fertilization to facilitate a normal pregnancy. It is an evolving technique which offers a practical alternative to prenatal diagnosis for couples who might be at a risk of transmitting a genetic disorder to their offspring. The samples for performing the genetic testing are obtained after in vitro fertilization from cleaving embryos. In order to establish a pregnancy, only those embryos that are free from genetic disorders   are made available to be replaced in the uterus.
Preimplantation genetic diagnosis was originally conceived as an alternative to prenatal diagnosis. It was developed to reduce the chances of transmitting severe genetic disorders for couples with a serious reproductive risk. Embryos that are affected by a single gene disorder are usually viable, but subsequently, the children are at a risk of suffering from developmental delay or physical abnormalities.
Preimplantation genetic tests can be used for three distinct modes of genetic disorders. The first group involves single gene disorders. Such disorders can either be X-linked recessive, autosomal recessive or autosomal dominant. In such case, genetic linkage can be used to identify the embryos that are likely to remain unaffected. The second type involves X-linked disorders where there is a significant genetic heterogeneity or in which the particular gene defect might not be identified. The third category includes chromosomal rearrangements such as Robertsonian or reciprocal translocations.
The global preimplantation genetic testing market is primarily driven by factors such as increasing rate of infertility as a result of changing lifestyle of people around the world, recent technological innovations in the field of genetic testing and analysis and increase in investment by governments as well as biotechnology companies in preimplantation genetic testing. Rising incidence of various gene-related diseases is also expected to largely contribute to the growth of the overall market. However, factors such as unfavorable regulatory policies and high procedure cost incurred for preimplantation genetic diagnosis can hamper the market growth during the forecast period.
Major Market Players
·         Illumina Inc.
·         Thermo Fisher Scientific Inc.
·         PerkinElmer Inc.
·         Cooper Surgical Inc.
·      Abbott Laboratories Inc.
·         Agilent Technologies Inc.
·         Natera Inc.
·         Rubicon Genomics Inc. (acquired by Takara Bio USA Holdings, Inc.)
·         Yikon Genomics
·         Oxford Gene Technology Group
·         SciGene Corporation
·         INVICTA GENETICS
·         Good Start Genetics Inc.
Preimplantation Genetic Testing Market Segmentation:
By Technology:
  • Polymerase Chain Reaction (PCR)
  • Fluorescent In-situ Hybridization (FISH)
  • Next Generation Sequencing (NGS)
  • Single Nucleotide Polymorphism (SNP)
  • Comparative Genomic Hybridization (CGH)
By Application:
  • Single Gene Disorders
  • Aneuploidy
  • HLA Typing
  • Structural Chromosomal Abnormalities
o    Deletions
o    Translocations
o    Inversions
o    Duplications
  • Gender Identification
By Procedure Type
  • Preimplantation Genetic Diagnosis
  • Preimplantation Genetic Screening
By Product and Service
  • Instruments
  • Reagents & Consumables
  • Software & Services
By End User:
  • Maternity Centers & Fertility Clinics
  • Research Laboratories & Academic Institutes
  • Hospitals, Diagnostic Labs, and Service Providers
By Region:
  • North America
o    U.S
o    Canada
o    Mexico
  • Europe
o    Germany
o    France
o    UK
o    Italy
o    Spain
o    Rest of Europe
  • Asia-Pacific
o    Japan
o    China
o    Australia
o    India
o    South Korea
o    Rest of Asia-Pacific
  • Rest of the World
o    Brazil
o    South Africa
o    Saudi Arabia
o    Turkey
o    United Arab Emirates
o    Others

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