Smart Insulin Or Glucose Responsive Insulin Market 2022 Emerging Trends
Diabetes is a disease in which the body either doesn't make
enough insulin or can't utilize the produced insulin. In diabetes blood glucose
level is high. Polyuria, polydipsia, polyphagia, dry skin and tingling
sensation in hands or feet are symptoms of diabetes. There are three types of
diabetes, namely, type 1 (insulin dependent), type 2 diabetes (insulin
independent) and gestational diabetes. In type 1 diabetes, the part of pancreas
is attacked by body’s immune system. By mistake, the immune system destroys
islets in the pancreas assuming them as foreign particles. The islets are the
insulin producing cells. Causes for type 1 diabetes are diseases of the
pancreas, infections and family history. In type 2 diabetes, insulin is
produced in less quantity but it’s not enough to maintain optimum blood
glucose. Causes of type 2 diabetes are obesity or overweight, ethnicity,
gestational diabetes, age, sedentary lifestyle, impaired glucose tolerance,
family history and insulin resistance. Gestational diabetes develops only
during pregnancy.
Diabetes is controlled by delivering insulin or with the
help of anti diabetic drugs. Insulin is released by the beta cells in response
to the high blood glucose levels. Insulin thus allows maintenance of blood
glucose level in optimum range. In type 1-diabetes, the body no longer produces
enough insulin as beta cells are destroyed. Thus controlling the blood sugar
level is challenging aspect in management of type 1 diabetes. In such a case
smart insulin can be used. A perfect glucose control will be maintained by
smart insulin. Smart
Insulin Or Glucose Responsive Insulin has ability to circulate in the body.
It would respond automatically to level of blood glucose in the body. It can
turn on when it’s needed and off when it’s not needed. If the blood glucose is
higher, more insulin will be released or activated. If the blood glucose level
is lower, less insulin will be released. Smart insulin will avoid the
complications related to high and low blood sugar levels. It will reduce the
requirement of checking the blood glucose level regularly. It will also reduce
the efforts of calculating insulin doses and multiple daily injections.
Smart insulin will give confidence to type 1 diabetes patients, that to cover
their needs for the day they have enough insulin no matter how rigorously they
work, what or how stressed they are.
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The major driving factor for the Smart insulin market is increase in
diabetic population. For instance, according to IDF, in 2015, diabetes affected
415 million people worldwide and this number is expected to reach up to 642
million by 2040. Moreover, it was found that one in 11 adults was suffering
from diabetes. Moreover, rise in the collaboration of companies with research
institutions will further drive this market. For instance in March 2016, JDRF
and Sanofi announced expansion of their joint research collaboration to include
development of glucose responsive insulin therapies for treatment of insulin
dependent diabetes. The aim of this collaboration is to design therapeutic
insulin which gets activated when blood-glucose levels rise and deactivated
when blood-glucose levels begin to go low, thus preventing dangerous highs and
lows. Moreover, technological improvements in the insulin delivery devices will
also contribute to growth of this market. Further, insulin injections are
painful and thus there is a rise in demand by people for alternatives such as
smart insulin. This demand will boost the smart insulin market. Furthermore,
smart insulin patch will serve as an opportunity for this market. The smart
insulin patch will use painless micro needles to recognize the low oxygen
environment which will be created when glucose levels rise. Further, it will
deliver insulin as required. However, more complexities are associated in
manufacturing of smart insulin which will impede the growth of smart insulin
market. Moreover, huge investment cost in developing smart insulin and strict
regulatory requirements for approvals will also hamper the growth of this
market.
The key strategy followed by the major companies is
acquisition to be a pioneer in this market, as smart insulin is a new market
and players are looking to gain competitive advantage. For instance, in 2016,
Eli Lilly and Company acquired Glycostasis, Inc. Glycostasis, Inc. invented a
new technology known as smart insulin. This technology will help in regulating
blood glucose level by releasing more insulin when blood glucose level is high
and less insulin when blood glucose level is low. By this acquisition, Eli
Lilly and Company will become a pioneer in the smart insulin or glucose
responsive insulin market.
Major Market Players
Ø Sanofi
Ø Novo
Nordisk A/S
Ø Juvenile
Diabetes Research Foundation Ltd.
Ø Eli
Lilly and Company
Ø
Merck & Co., Inc.
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Smart
Insulin or Glucose Responsive Market Segmentation:
By
Type:
- Intermediate
Acting
- Short
Acting
- Premixed
Type
- Long
Acting
- Rapid
Acting
By
Disease:
- Type
1 Diabetes
- Type
2 Diabetes
By
Delivery Device:
- Smart
Insulin Patch or Microneedle Array Patch
- Smart
Insulin Pen
- Smart
Insulin Pump
By Region:
- North
America
o
U.S
o
Canada
o
Mexico
- Europe
o
Germany
o
France
o
UK
o
Italy
o
Spain
o
Rest of Europe
- Asia-Pacific
o
Japan
o
China
o
Australia
o
India
o
South Korea
o
Rest of Asia-Pacific
- Rest
of the World
o
Brazil
o
South Africa
o
Saudi Arabia
o
Turkey
o
United Arab Emirates
o
Others
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